T5.6 Use Case “Radiomics / Imaging AI”

T5.6 Use Case “Radiomics / Imaging AI”

Background

The Use case “Radiomics / Imaging AI” is led by the Fraunhofer MEVIS. The BIPS, the Fraunhofer FIT, the University of Cologne and the Leipzig University are involved as project partners.

Biomedical imaging has become an important area of data collection in epidemiologic and clinical studies because of its ability to detect both local and systemic changes, its high information density and its wide availability. Radiomics is defined as a method that uses pattern recognition and machine learning algorithms to extract large amounts of quantitative features from medical images.

Modern machine learning techniques, especially deep learning, combined with conventional data analysis within multidisciplinary healthcare data, promise to bring medical imaging closer to understanding complex diseases in a quantitative way by integrating clinical, structural, and imaging-based features.

Image

Radiomics discovers relationships between image features and clinical data. Copyright: Fraunhofer MEVIS

Objectives

In collaboration with TA3 “Services”, NFDI4Health infrastructure components will be implemented in this Use Case as a prototypical AI analysis test bed along the Radiomics paradigm, with the ultimate goal of standardising and validating AI for wider use. Where appropriate, the DICOM standard will be used to harmonise image data and associated metadata in accordance with TA2 “Standards for FAIR Data”.

In particular, a proof-of-concept for automated AI-supported quality assurance of DICOM image data will be implemented and evaluated in sub-cohorts of heterogeneous MR volume data as part of NFDI4Health. In addition, a demonstrator will be created that enables predictive pattern recognition in combined imaging and structured epidemiological data.

The long-term goal within NFDI4Health is to provide an AI-based pilot radiomics platform for the automated quality assurance and analysis of biomedical (image) data as a service for the community. The use of AI allows for easy adaptability to new application contexts and continuous optimisation, particularly through federated learning.

Fraunhofer MEVIS is cooperating with Grand Challenge (Grand-challenge.org), the world's largest platform for the exchange of benchmark datasets and AI models for biomedical imaging. The aim is to offer the community a German mirror node of Grand-challenge.org under the umbrella of NFDI4Health.

Publications

Pigeot I, Fröhlich H, Intemann T, Prause G, Wright MN. KI und die Nationale Forschungsdateninfrastruktur für personenbezogene Gesundheitsdaten (NFDI4Health). In: Dössel OS, Tobias; Rutert, Britta, editor. Künstliche Intelligenz in der Medizin. Denkanstöße aus der Akademie: Eine Schriftenreihe der Berlin-Brandenburgischen Akademie der Wissenschaften, Nr. 11. Berlin: Berlin-Brandenburgische Akademie der Wissenschaften; 2023. p. 62-74. https://edoc.bbaw.de/frontdoor/index/index/docId/3807

Mou Y, Li F, Weber S, Haneef, Meine H, Caldeira L, Jaberansary M, Welten S, Ucer YY, Prause G, Decker S, Beyan O, Kirsten T. Distributed Privacy-Preserving Data Analysis in NFDI4Health with the Personal Health Train. 1st Conference on Research Data Infrastructure (CoRDI), 12-14 September 2023, Karlsruhe. https://doi.org/10.52825/CoRDI.v1i.282

Floca R, Bohn J, Haux C, Wiestler B, Zöllner FG, Reinke A, Weiß J, Nolden M, Albert S, Persigehl T, Norajitra T, Baeßler B, Dewey M, Braren R, Büchert M, Fallenberg EM, Galldiks N, Gerken A, Götz M, Hahn HK, Haubold J, Haueise T, Große Hokamp N, Ingrisch M, Iuga A-I, Janoschke M, Jung M, Kiefer LS, Lohmann P, Machann J, Moltz JH, Nattenmüller J, Nonnenmacher T, Oerther B, Othman AE, Peisen F, Schick F, Umutlu L, Wichtmann BD, Zhao W, Caspers S, Schlemmer H-P, Schlett CL, Maier-Hein K, Bamberg F. Radiomics workflow definition & challenges – German priority program 2177 consensus statement on clinically applied radiomics. Insights into Imaging 15:124, 2024. https://doi.org/10.1186/s13244-024-01704-w

Contact

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Prof. Dr. Horst Hahn

Measure-Lead T5.6 “Use case Radiomics / imaging AI"

E-Mail: horst.hahn@mevis.fraunhofer.de Phone: +49 (0)421 218-59002

Fraunhofer Institute for Digital Medicine MEVIS
Max-von-Laue-Str. 2
28359 Bremen